Description

7,7-Difluoro-3-Azabicyclo[4.1.0]Heptane Hydrochloride is a high-value, synthetically challenging bicyclic amine hydrochloride salt featuring a unique difluorinated cyclopropane ring system. This compound serves as a critical pharmaceutical intermediate and versatile building block in medicinal chemistry for the development of novel bioactive molecules. It is primarily sought by R&D and process chemistry teams in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Building Block: Used to introduce the rigid, polar 3-azabicyclo[4.1.0]heptane scaffold with fluorine atoms, which can enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Research: Employed in the discovery and development of new generation herbicides and pesticides with improved efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral amines and ligands used in asymmetric synthesis.
• Chemical Biology Probe Synthesis: Utilized to create tool compounds for studying enzyme function and biological pathways.
• Advanced Material Synthesis: Potential monomer or additive for creating specialty polymers with unique properties.

Basic Information

Product Name	7,7-Difluoro-3-Azabicyclo[4.1.0]Heptane Hydrochloride
CAS No.	1376248-54-2
Molecular Formula	C6H10ClF2N
Molecular Weight	169.60 g/mol
Synonyms	3-Azabicyclo[4.1.0]heptane, 7,7-difluoro-, hydrochloride; 7,7-Difluoro-3-azabicyclo[4.1.0]heptane HCl; 7,7-Difluoro-3-azabicyclo[4.1.0]heptane hydrochloride; 7,7-Difluoro-3-azoniabicyclo[4.1.0]heptane chloride; Difluorinated 3-Azabicyclo[4.1.0]heptane Hydrochloride
EINECS	Contact for details

Quality Control

Our 7,7-Difluoro-3-Azabicyclo[4.1.0]Heptane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Titration)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.