Description

4,5,6,7-Tetrahydro-2H-Indazol-3-Ylamine Dihydrochloride is a high-purity, pharmaceutically relevant chemical building block. This compound is a crucial intermediate in the synthesis of novel therapeutic agents, particularly in the development of kinase inhibitors and other small molecule drugs. It is primarily utilized by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of kinase inhibitors targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Chemical Biology Probes: Serves as a core scaffold for developing selective probes to study enzyme function and cellular signaling.
• Process Chemistry & Scale-Up: Employed in route scouting and pilot-scale synthesis for active pharmaceutical ingredient (API) manufacturing.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and pre-clinical development services.

Basic Information

Product Name	4,5,6,7-Tetrahydro-2H-Indazol-3-Ylamine Dihydrochloride
CAS No.	1376043-30-9
Molecular Formula	C7H13Cl2N3
Molecular Weight	210.11 g/mol
Synonyms	3-Amino-4,5,6,7-tetrahydro-2H-indazole dihydrochloride; 4,5,6,7-Tetrahydro-1H-indazol-3-amine dihydrochloride; 3-Amino-4,5,6,7-tetrahydroindazole dihydrochloride; 2H-Indazol-3-amine, 4,5,6,7-tetrahydro-, dihydrochloride; 1376043-30-9; 4,5,6,7-Tetrahydro-2H-indazol-3-ylamine dihydrochloride
EINECS	Contact for details

Quality Control

Our 4,5,6,7-Tetrahydro-2H-Indazol-3-Ylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with every shipment. We support development projects with custom purity grades and analytical method development upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.