Description

Xantphos-Pd-G2 CAS NO 1375325-77-1 is a highly active, second-generation palladium catalyst pre-ligated with the Xantphos ligand, designed for superior performance in demanding cross-coupling reactions. This preformed complex offers exceptional convenience, stability, and reproducibility, eliminating the need for in-situ ligand mixing and ensuring consistent catalytic activity. It is an indispensable tool for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable and efficient catalysis for complex synthesis.

Application

• Pharmaceutical Intermediate Synthesis: Enables key carbon-carbon and carbon-heteroatom bond formations (e.g., Buchwald-Hartwig amination, Suzuki-Miyaura coupling) in API development.
• Agrochemical Production: Used in the synthesis of complex, bioactive molecules for crop protection agents.
• Fine Chemical Manufacturing: Facilitates scalable, high-yield coupling reactions for specialty and performance chemicals.
• Polymer & Materials Science: Catalyzes polymerization and functionalization reactions to create novel polymers and electronic materials.
• Methodology Development & Catalysis Research: A preferred catalyst for exploring new reaction pathways due to its defined structure and reliable activity.
• Process Chemistry & Scale-up: Ideal for transitioning from lab-scale discovery to pilot and commercial manufacturing, offering robust performance.

Basic Information

Product Name	Xantphos-Pd-G2
CAS No.	1375325-77-1
Molecular Formula	C39H38Cl2P2Pd
Molecular Weight	746.45 g/mol
Synonyms	Chloro(2-dicyclohexylphosphino-2',4',6'-triisopropyl-1,1'-biphenyl)[2-(2-aminoethyl)phenyl]palladium(II); Chloro[2-(dicyclohexylphosphino)-2',4',6'-triisopropyl-1,1'-biphenyl][2-(2-aminoethyl)phenyl]palladium(II); Pd(Xantphos) G2; Xantphos Palladacycle Gen. 2; XPhos Pd G2 (related but distinct); BrettPhos Pd G3 (related but distinct); Palladium Xantphos Precatalyst; [2-(2-Aminoethyl)phenyl]chloropalladium-Xantphos complex
EINECS	Contact for details

Quality Control

Our Xantphos-Pd-G2 is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as palladium content, ligand assay, and impurity profiles. We adhere to cGMP principles where applicable and support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and prevent decomposition. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange-brown solid
Identification (IR)	Conforms to structure
Palladium (Pd) Content	13.5 - 15.0 %
Purity (HPLC)	≥ 95.0%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.