Description

Ethyl 3-Aminocyclobutanecarboxylate Hcl is a high-purity, pharmaceutically relevant building block characterized by its cyclobutane core and ester-protected amino acid functionality. This compound is of significant value in medicinal chemistry for constructing novel molecular scaffolds with constrained geometries. It is primarily sought after by research and development teams in the pharmaceutical and biotechnology sectors for use in drug discovery programs, particularly in the synthesis of potential protease inhibitors, receptor modulators, and other bioactive small molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new chemical space for drug candidates.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the design of inhibitors for various enzymatic targets.
• Peptidomimetics Synthesis: Employed to create conformationally restricted peptide analogs with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Academic & Contract Research: Essential for synthetic organic chemistry research in academic institutions and contract research organizations (CROs).

Basic Information

Item	Details
Product Name	Ethyl 3-Aminocyclobutanecarboxylate Hydrochloride
CAS No.	1375303-78-8
Molecular Formula	C7H14ClNO2
Molecular Weight	179.64 g/mol
Synonyms	Ethyl 3-aminocyclobutanecarboxylate hydrochloride; 3-Aminocyclobutanecarboxylic acid ethyl ester hydrochloride; Ethyl 3-aminocyclobutanecarboxylate HCl; 1-Aminocyclobutane-3-carboxylic acid ethyl ester hydrochloride; Cyclobutane-3-carboxylic acid, 3-amino-, ethyl ester, hydrochloride; Ethyl 3-amino-1-cyclobutanecarboxylate hydrochloride; (3-Aminocyclobutyl)carboxylic acid ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl 3-Aminocyclobutanecarboxylate Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable material for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.