Description

7'-Methyl-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-isoquinoline] is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic isoquinoline class of compounds. This compound matters as a critical building block for medicinal chemistry research, enabling the synthesis of novel drug candidates with complex three-dimensional architectures. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutics, particularly in the areas of central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening for drug discovery.
• Organic Synthesis Building Block: Employed in the synthesis of complex spirocyclic and polycyclic molecules for material science and chemical biology.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional laboratories for studying novel chemical reactions and biological activity.

Basic Information

Product Name	7'-Methyl-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-isoquinoline]
CAS No.	1375303-76-6
Molecular Formula	C13H17N
Molecular Weight	187.28 g/mol
Synonyms	7'-Methyl-1'H-spiro[cyclobutane-1,4'-isoquinoline]-2',3'-dihydro; 1'H-Spiro[cyclobutane-1,4'-isoquinoline], 2',3'-dihydro-7'-methyl-; Spiro[cyclobutane-1,4'-isoquinoline], 7'-methyl-2',3'-dihydro-1'H-; 7-Methyl-2,3-dihydro-1H-spiro[cyclobutane-1,4'-isoquinoline]; 1375303-76-6; 7'-Methylspiro[cyclobutane-1,4'-isoquinoline]-2',3'-dihydro; Spirocyclic isoquinoline derivative
EINECS	Contact for details

Quality Control

Our 7'-Methyl-2',3'-dihydro-1'H-spiro[cyclobutane-1,4'-isoquinoline] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.