Description

6-Bromo-7-Chloro-8-Fluoroquinoline is a high-purity, multi-halogenated quinoline derivative serving as a critical advanced pharmaceutical intermediate. Its unique halogen substitution pattern makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in the development of next-generation antibacterial and antiviral agents. This compound is essential for research and production in pharmaceutical R&D, agrochemical synthesis, and advanced material science, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex fluoroquinolone antibiotics and other therapeutic agents targeting bacterial DNA gyrase and topoisomerase IV.
• Agrochemical Research: Used in the development of new-generation fungicides and bactericides with enhanced efficacy and environmental profiles.
• Chemical Synthesis Building Block: Employed in organic synthesis for constructing complex heterocyclic compounds due to its reactive halogen sites.
• Material Science: Investigated as a precursor for organic electronic materials and functional dyes, leveraging the quinoline core's electronic properties.
• Academic & Industrial R&D: Serves as a standard or starting material in medicinal chemistry programs for drug discovery and process development.

Basic Information

Product Name	6-Bromo-7-Chloro-8-Fluoroquinoline
CAS No.	1375069-04-7
Molecular Formula	C9H4BrClFN
Molecular Weight	260.49 g/mol
Synonyms	8-Fluoro-6-bromo-7-chloroquinoline; 6-Bromo-7-chloro-8-fluoroquinoline; Quinoline, 6-bromo-7-chloro-8-fluoro-; 1375069-04-7; 8-Fluoro-7-chloro-6-bromoquinoline; 7-Chloro-6-bromo-8-fluoroquinoline
EINECS	Contact for details

Quality Control

Our 6-Bromo-7-Chloro-8-Fluoroquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.