Description

{3-[3-(Methylcarbamoyl)Phenyl]Phenyl}Acetic Acid CAS NO 1375068-89-5 is a high-purity, non-natural amino acid derivative featuring a biphenyl acetic acid core with a methylcarbamoyl substituent. This compound is a critical pharmaceutical intermediate and research chemical used in the synthesis of advanced active pharmaceutical ingredients (APIs) and novel bioactive molecules. It is essential for medicinal chemistry research, process development, and scale-up manufacturing in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting inflammation, metabolic disorders, and central nervous system (CNS) diseases.
• Protease Inhibitor Development: Used in research for designing and optimizing inhibitors for specific enzyme targets due to its structural similarity to peptide motifs.
• Chemical Biology & Proteomics: Serves as a versatile scaffold or linker for creating chemical probes to study protein function and biological pathways.
• Peptidomimetic Synthesis: Integral component in the development of peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Material Science Research: Potential monomer or functional additive in the development of specialized polymers with targeted properties.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and custom synthesis facilities for client-specific projects and library synthesis.

Basic Information

Product Name	{3-[3-(Methylcarbamoyl)Phenyl]Phenyl}Acetic Acid
CAS No.	1375068-89-5
Molecular Formula	C16H15NO3
Molecular Weight	269.30 g/mol
Synonyms	2-{3-[3-(Methylaminocarbonyl)phenyl]phenyl}acetic acid; [3'-(N-Methylcarbamoyl)[1,1'-biphenyl]-3-yl]acetic acid; 3'-(Methylcarbamoyl)biphenyl-3-acetic acid; Biphenyl-3-acetic acid, 3'-(methylcarbamoyl)-; (3'-(Methylcarbamoyl)-[1,1'-biphenyl]-3-yl)acetic acid; N-Methyl-3'-(carboxymethyl)biphenyl-3-carboxamide
EINECS	Contact for details

Quality Control

Our {3-[3-(Methylcarbamoyl)Phenyl]Phenyl}Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.