Description

5-Bromo-2-Fluoro-3-Nitrotoluene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective and sequential functionalization, making it a critical intermediate in the development of complex molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the bromo and fluoro substituents enhance biological activity.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro group and halogen atoms.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations, enabling the introduction of diverse functional groups.
• Dye and Pigment Intermediate: Utilized in the development of specialized colorants and photographic chemicals.
• Academic & Contract Research: A valuable reagent for methodological studies and library synthesis in academic and contract research organizations (CROs).

Basic Information

Product Name	5-Bromo-2-Fluoro-3-Nitrotoluene
CAS No.	1375068-74-8
Molecular Formula	C7H5BrFNO2
Molecular Weight	234.03 g/mol
Synonyms	1-Bromo-4-fluoro-2-methyl-5-nitrobenzene; 2-Methyl-5-bromo-4-fluoro-1-nitrobenzene; 3-Nitro-5-bromo-2-fluorotoluene; Toluene, 5-bromo-2-fluoro-3-nitro-; 5-Bromo-2-fluoro-3-nitro-1-methylbenzene
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Fluoro-3-Nitrotoluene is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.