Description

1-Bromo-5-Fluoro-2-Isopropoxy-3-Nitrobenzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound is valued for its unique substitution pattern, which provides multiple reactive sites for constructing complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogen and nitro functional groups.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution (SNAr) to introduce complex aryl ether motifs.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing specialized nitro- and halogen-substituted dyes.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and library development for client projects.

Basic Information

Product Name	1-Bromo-5-Fluoro-2-Isopropoxy-3-Nitrobenzene
CAS No.	1375068-62-4
Molecular Formula	C9H9BrFNO3
Molecular Weight	278.08 g/mol
Synonyms	2-Bromo-4-fluoro-1-isopropoxy-5-nitrobenzene; 4-Fluoro-2-bromo-1-isopropoxy-5-nitrobenzene; Benzene, 1-bromo-5-fluoro-2-(1-methylethoxy)-3-nitro-; 1-Isopropoxy-2-bromo-4-fluoro-5-nitrobenzene; 5-Fluoro-2-bromo-1-isopropoxy-3-nitrobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-5-Fluoro-2-Isopropoxy-3-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade starting materials and ensures reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.