Description

2(1H)-Quinolinone, 6-Bromo-8-Methyl-4-(Trifluoromethyl)- is a high-purity, halogenated quinolinone derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique trifluoromethyl and bromo substituents make it a valuable building block for introducing specific functionalities into target molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for oncology, CNS, and anti-infective therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient quinolinone core.
• Chemical Biology Probes: Employed in the synthesis of fluorescent tags and molecular probes for studying biological processes.
• Catalyst & Ligand Development: Acts as a scaffold for designing novel ligands and catalysts in asymmetric synthesis and cross-coupling reactions.

Basic Information

Product Name	2(1H)-Quinolinone, 6-Bromo-8-Methyl-4-(Trifluoromethyl)-
CAS No.	1375066-09-3
Molecular Formula	C11H7BrF3NO
Molecular Weight	306.08 g/mol
Synonyms	6-Bromo-8-methyl-4-(trifluoromethyl)quinolin-2(1H)-one; 6-Bromo-8-methyl-4-(trifluoromethyl)-1H-quinolin-2-one; 6-Bromo-8-methyl-4-(trifluoromethyl)-2(1H)-quinolinone; 4-(Trifluoromethyl)-6-bromo-8-methyl-2(1H)-quinolinone; 6-Bromo-8-methyl-4-trifluoromethyl-2-quinolone; 1375066-09-3; 6-Bromo-8-methyl-4-(trifluoromethyl)-2-quinolone
EINECS	Contact for details

Quality Control

Our 2(1H)-Quinolinone, 6-Bromo-8-Methyl-4-(Trifluoromethyl)- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.