Description

1-(3-Bromo-5-Chloropyrazin-2-Yl)Hydrazine is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique pyrazine core enables precise molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functionalized hydrazine and halogenated pyrazine motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated pyrazine structure.
• Ligand and Catalyst Development: Employed in organometallic chemistry for creating specialized ligands used in catalytic processes.
• Material Science Research: Acts as a building block for organic electronic materials and functional polymers.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services.
• Academic and Industrial R&D: Utilized in exploratory chemistry for constructing complex heterocyclic libraries for screening.

Basic Information

Product Name	1-(3-Bromo-5-Chloropyrazin-2-Yl)Hydrazine
CAS No.	1374652-24-0
Molecular Formula	C4H4BrClN4
Molecular Weight	223.46 g/mol
Synonyms	1-(3-Bromo-5-chloropyrazin-2-yl)hydrazine; (3-Bromo-5-chloro-2-pyrazinyl)hydrazine; 2-Hydrazinyl-3-bromo-5-chloropyrazine; 3-Bromo-5-chloropyrazin-2-ylhydrazine; Hydrazine, 1-(3-bromo-5-chloropyrazin-2-yl)-; 1374652-24-0; 1-(3-Bromo-5-chloro-pyrazin-2-yl)-hydrazine
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-5-Chloropyrazin-2-Yl)Hydrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.