Description

1-(Tetrahydro-2H-Thiopyran-4-Yl)Hydrazine Dihydrochloride is a specialized organic building block and intermediate of significant interest in advanced chemical synthesis. This compound is valued for its unique heterocyclic structure, which incorporates a sulfur-containing thiopyran ring and a reactive hydrazine moiety, making it a versatile precursor for the development of novel pharmacologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of new chemical entities targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new active pharmaceutical ingredients (APIs), especially for compounds containing saturated sulfur heterocycles.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and synthesize novel scaffolds for biological screening.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, or insecticides that leverage the thiopyran structure.
• Ligand and Catalyst Development: The hydrazine group can be functionalized to create novel chelating ligands for metal catalysis or organocatalysts.
• Chemical Biology Probes: Useful for synthesizing molecular probes to study enzyme function or biological pathways in research settings.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds at various scales.

Basic Information

Product Name	1-(Tetrahydro-2H-Thiopyran-4-Yl)Hydrazine Dihydrochloride
CAS No.	1374652-09-1
Molecular Formula	C5H13Cl2N2S
Molecular Weight	211.14 g/mol
Synonyms	4-Hydrazinyltetrahydro-2H-thiopyran dihydrochloride; Tetrahydro-2H-thiopyran-4-ylhydrazine dihydrochloride; 1-(Tetrahydro-2H-thiopyran-4-yl)hydrazine hydrochloride (1:2); 4-Hydrazinothiane dihydrochloride; Thiopyran-4-ylhydrazine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Tetrahydro-2H-Thiopyran-4-Yl)Hydrazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure the material meets your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.