Description

8-Naphthyridin-2(1H)-One is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Precursor: Acts as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for method development and novel compound library synthesis.

Basic Information

Product Name	8-Naphthyridin-2(1H)-One
CAS No.	1374651-58-7
Molecular Formula	C8H6N2O
Molecular Weight	146.15 g/mol
Synonyms	2(1H)-Naphthyridinone; 1,8-Naphthyridin-2(1H)-one; 1H-1,8-Naphthyridin-2-one; 8-Hydroxy-1,8-naphthyridine; 1,8-Naphthyridin-2-ol; 2-Hydroxy-1,8-naphthyridine
EINECS	Contact for details

Quality Control

Our 8-Naphthyridin-2(1H)-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.