Description

Methyl 2-[(E)-2-(Dimethylamino)Vinyl]-6-Isopropyl-5-Oxo-5,6-Dihydro-1,6-Naphthyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex naphthyridine core structure. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by research institutions, custom synthesis laboratories, and pharmaceutical companies engaged in the development of new drug candidates, especially within oncology and antiviral research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of complex drug molecules and investigational new drugs.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing naphthyridine-based heterocyclic compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Custom Synthesis: Supplied to contract research and manufacturing organizations (CROs/CMOs) for client-specific synthesis projects.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	Methyl 2-[(E)-2-(Dimethylamino)Vinyl]-6-Isopropyl-5-Oxo-5,6-Dihydro-1,6-Naphthyridine-3-Carboxylate
CAS No.	1374510-92-5
Molecular Formula	C18H23N3O3
Molecular Weight	329.40 g/mol
Synonyms	Methyl (2E)-2-[2-(dimethylamino)ethenyl]-6-(1-methylethyl)-5-oxo-1,6-dihydro-1,6-naphthyridine-3-carboxylate; 1,6-Naphthyridine-3-carboxylic acid, 5,6-dihydro-2-[(1E)-2-(dimethylamino)ethenyl]-6-(1-methylethyl)-5-oxo-, methyl ester; 1374510-92-5; Methyl 2-((E)-2-(dimethylamino)vinyl)-6-isopropyl-5-oxo-5,6-dihydro-1,6-naphthyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the exact specifications and results. We support our clients' regulatory needs with traceable documentation suitable for use in cGMP-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.