Description

1-[7-[(E)-2-(Dimethylamino)Vinyl]-2-(Trifluoromethyl)-[1,2,4]Triazolo[1,5-A]Pyrimidin-6-Yl]Ethano is a high-value, structurally complex heterocyclic compound featuring a triazolopyrimidine core, a trifluoromethyl group, and a dimethylaminovinyl substituent. This molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in oncology and antiviral therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new pesticides and herbicides, leveraging the biological activity of the triazolopyrimidine scaffold.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and biological pathways.
• Material Science: Potential component in the development of advanced organic electronic materials due to its conjugated system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Item	Detail
Product Name	1-[7-[(E)-2-(Dimethylamino)Vinyl]-2-(Trifluoromethyl)-[1,2,4]Triazolo[1,5-A]Pyrimidin-6-Yl]Ethano
CAS No.	1374510-76-5
Molecular Formula	C13H13F3N6O
Molecular Weight	326.28 g/mol
Synonyms	1-[7-[(E)-2-(Dimethylamino)ethenyl]-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]ethanone; 2-(Trifluoromethyl)-7-[(E)-2-(dimethylamino)vinyl]-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl methyl ketone; 1374510-76-5; Ethanone, 1-[7-[(E)-2-(dimethylamino)ethenyl]-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl]-; (E)-1-(7-(2-(Dimethylamino)vinyl)-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our production of 1-[7-[(E)-2-(Dimethylamino)Vinyl]-2-(Trifluoromethyl)-[1,2,4]Triazolo[1,5-A]Pyrimidin-6-Yl]Ethano adheres to stringent ISO 9001 quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Custom synthesis and purity grades (e.g., >95%, >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Standard Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.