Description

4-(Bromomethyl)-1-(4-Fluorobenzoyl)-2,2-Dimethyl-1,2-Dihydroquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its unique quinoline-based structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, offering a versatile bromomethyl handle for further functionalization. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• API Synthesis: Used in the development and production of Active Pharmaceutical Ingredients (APIs) for various therapeutic areas.
• Agrochemical Research: Serves as a precursor in the creation of new pesticides and herbicides.
• Chemical Biology: Employed as a probe or linker in biochemical and proteomic studies due to its reactive bromomethyl group.
• Material Science: Potential monomer or precursor for the synthesis of functional polymers and advanced materials.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs to create bespoke compounds for client projects.

Basic Information

Product Name	4-(Bromomethyl)-1-(4-Fluorobenzoyl)-2,2-Dimethyl-1,2-Dihydroquinoline
CAS No.	1374509-75-7
Molecular Formula	C20H19BrFNO
Molecular Weight	388.28 g/mol
Synonyms	1-(4-Fluorobenzoyl)-4-(bromomethyl)-2,2-dimethyl-1,2-dihydroquinoline; 4-(Bromomethyl)-2,2-dimethyl-1-(4-fluorobenzoyl)-1,2-dihydroquinoline; Quinoline, 1,2-dihydro-4-(bromomethyl)-1-[(4-fluorophenyl)carbonyl]-2,2-dimethyl-; 1374509-75-7; 4-Bromomethyl-1-(4-fluorobenzoyl)-2,2-dimethyl-1,2-dihydroquinoline
EINECS	Contact for details

Quality Control

Our 4-(Bromomethyl)-1-(4-Fluorobenzoyl)-2,2-Dimethyl-1,2-Dihydroquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.