Description

Ethyl [4-(4-Chlorophenyl)-2,4-Dimethyl-3,4-Dihydroquinolin-1(2H)-Yl](Oxo)Acetate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1374509-57-5. This compound is a critical building block in modern medicinal chemistry, valued for its complex heterocyclic structure that enables the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory targets.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel quinoline-based drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic discovery.
• API Development: Serves as a core scaffold in the development of potential APIs targeting neurological disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up for clinical trial materials.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Ethyl [4-(4-Chlorophenyl)-2,4-Dimethyl-3,4-Dihydroquinolin-1(2H)-Yl](Oxo)Acetate
CAS No.	1374509-57-5
Molecular Formula	C21H22ClNO3
Molecular Weight	371.86 g/mol
Synonyms	Ethyl 2-[4-(4-chlorophenyl)-2,4-dimethyl-3,4-dihydro-2H-quinolin-1-yl]-2-oxoacetate; 1,2,3,4-Tetrahydro-4-(4-chlorophenyl)-2,4-dimethyl-1-oxo-2-quinolineacetic Acid Ethyl Ester; Ethyl (4-(4-Chlorophenyl)-2,4-dimethyl-3,4-dihydroquinolin-1(2H)-yl)(oxo)acetate; 1374509-57-5; Quinoline-1-acetic acid derivative
EINECS	Contact for details

Quality Control

Our Ethyl [4-(4-Chlorophenyl)-2,4-Dimethyl-3,4-Dihydroquinolin-1(2H)-Yl](Oxo)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.