Description

1-n-Boc-2-Nitroethanamine is a protected amine building block of significant value in synthetic organic chemistry. Its core utility lies in providing a versatile nitroethylamine synthon where the primary amine is safeguarded by a Boc (tert-butoxycarbonyl) group, enabling selective deprotection and further functionalization. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of complex molecules, active pharmaceutical ingredients (APIs), and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing nitro and amine functionalities.
• Peptidomimetics & Conjugate Synthesis: Used in the preparation of modified peptides and bioconjugates where the nitro group can be reduced to an amine for further coupling.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, insecticides, and fungicides.
• Material Science: Employed in the synthesis of specialty polymers, dendrimers, and functional materials that require precise amine incorporation.
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological pathways and enzyme activity.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic routes in organic chemistry.

Basic Information

Product Name	1-n-Boc-2-Nitroethanamine
CAS No.	1374160-25-4
Molecular Formula	C7H14N2O4
Molecular Weight	190.20 g/mol
Synonyms	2-Nitroethylcarbamic Acid tert-Butyl Ester; tert-Butyl (2-Nitroethyl)carbamate; N-Boc-2-Nitroethylamine; N-(tert-Butoxycarbonyl)-2-nitroethylamine; Boc-Nitroethylamine; (2-Nitroethyl)carbamic Acid 1,1-Dimethylethyl Ester; 1-Boc-2-Nitroethanamine; N-Boc-2-Nitroethanamine
EINECS	Contact for details

Quality Control

Our 1-n-Boc-2-Nitroethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.