Description

1-[2-Fluoro-3-(Trifluoromethyl)Phenyl]Ethan-1-Amine Hydrochloride is a high-purity, fluorinated aromatic amine hydrochloride salt, a key building block in advanced organic synthesis. This compound is valued for its unique trifluoromethyl and fluorine substituents, which are critical for modulating the physicochemical and metabolic properties of target molecules. It is primarily utilized by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a key precursor in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Used in the creation of specialty polymers, liquid crystals, and advanced organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Biology & Proteomics: Employed as a reagent for labeling and modifying biomolecules, facilitating studies in drug discovery and diagnostic development.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex molecules under cGMP or research-grade conditions.

Basic Information

Product Name	1-[2-Fluoro-3-(Trifluoromethyl)Phenyl]Ethan-1-Amine Hydrochloride
CAS No.	1373865-76-9
Molecular Formula	C9H8ClF4N
Molecular Weight	241.61 g/mol
Synonyms	1-(2-Fluoro-3-(trifluoromethyl)phenyl)ethanamine hydrochloride; α-Methyl-2-fluoro-3-(trifluoromethyl)benzylamine hydrochloride; 1-(2-Fluoro-3-trifluoromethylphenyl)ethylamine HCl; 2-Fluoro-α-methyl-3-(trifluoromethyl)benzenemethanamine hydrochloride; 1-Aminoethyl-2-fluoro-3-trifluoromethylbenzene hydrochloride; (1-(2-Fluoro-3-(trifluoromethyl)phenyl)ethyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[2-Fluoro-3-(Trifluoromethyl)Phenyl]Ethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring research-grade to cGMP-compliant materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.