Description

1-(2-Fluoro-5-(Trifluoromethyl)Phenyl)Ethanamine Hydrochloride is a high-purity, fluorinated aromatic amine hydrochloride salt, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity and electronic properties imparted by the fluorine and trifluoromethyl substituents, enabling the development of novel compounds with enhanced biological activity and stability. This intermediate is primarily required by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by fine chemical manufacturers producing specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for CNS agents, anti-inflammatories, and antiviral compounds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorine motifs improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, or organic electronic materials requiring fluorinated aromatic units.
• Chemical Biology Probes: Useful for labeling or modifying biomolecules in diagnostic and research applications.

Basic Information

Product Name	1-(2-Fluoro-5-(Trifluoromethyl)Phenyl)Ethanamine Hydrochloride
CAS No.	1373865-26-9
Molecular Formula	C9H8ClF4N
Molecular Weight	241.61 g/mol
Synonyms	1-(2-Fluoro-5-(trifluoromethyl)phenyl)ethan-1-amine hydrochloride; α-Methyl-2-fluoro-5-(trifluoromethyl)benzylamine hydrochloride; 1-(2-Fluoro-α-methyl-5-(trifluoromethyl)benzyl)amine hydrochloride; 2-Fluoro-α-methyl-5-(trifluoromethyl)benzylamine HCl; 1-(2-Fluoro-5-trifluoromethyl-phenyl)-ethylamine hydrochloride; (1-(2-Fluoro-5-(trifluoromethyl)phenyl)ethyl)amine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Fluoro-5-(Trifluoromethyl)Phenyl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.