Description

6-Benzyloxy-4-Hydroxy-Quinoline-2-Carboxylic Acid Methyl Ester is a high-purity, synthetic organic compound belonging to the quinoline carboxylic acid ester class, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its functionalized quinoline core, which is a privileged scaffold for designing bioactive molecules with potential therapeutic applications. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinoline-based drug candidates targeting various diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new therapeutic agents.
• Agrochemical Synthesis: Intermediate in the development of new crop protection agents and pesticides.
• Chemical Biology Probes: Serves as a precursor for fluorescent tags or molecular probes used in biochemical assays.
• Organic Synthesis Reference Standard: Used as a pure reference material in analytical method development and validation.
• Process Chemistry Development: Employed in scaling up synthetic routes for the commercial production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	6-Benzyloxy-4-Hydroxy-Quinoline-2-Carboxylic Acid Methyl Ester
CAS No.	1373835-19-8
Molecular Formula	C19H15NO4
Molecular Weight	321.33 g/mol
Synonyms	Methyl 6-(benzyloxy)-4-hydroxyquinoline-2-carboxylate; 6-Benzyloxy-4-hydroxy-2-quinolinecarboxylic acid methyl ester; 4-Hydroxy-6-benzyloxyquinoline-2-carboxylic acid methyl ester; 6-O-Benzyl-4-hydroxyquinoline-2-carboxylic acid methyl ester; Quinoline-2-carboxylic acid, 6-(benzyloxy)-4-hydroxy-, methyl ester; Methyl 4-hydroxy-6-(phenylmethoxy)-2-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our 6-Benzyloxy-4-Hydroxy-Quinoline-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.