Description

4-Bromo-Quinazoline Hydrobromide is a high-purity organic salt derivative of the quinazoline heterocycle, serving as a critical building block in advanced chemical synthesis. Its value lies in providing a reactive bromine handle and a stable salt form, which is essential for precise and efficient downstream modifications. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), kinase inhibitors, and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly kinase inhibitors for oncology and inflammatory diseases.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinazoline scaffold into more complex molecular architectures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries for biological screening.
• Agrochemical Research: Serves as an intermediate in the development of new herbicides and fungicides that utilize heterocyclic chemistry.
• Material Science Precursor: Investigated for the synthesis of organic semiconductors and light-emitting materials due to the quinazoline core's electronic properties.

Basic Information

Product Name	4-Bromo-Quinazoline Hydrobromide
CAS No.	1373223-20-1
Molecular Formula	C8H6BrN2•HBr
Molecular Weight	289.96 g/mol
Synonyms	4-Bromoquinazoline Hydrobromide; Quinazoline, 4-bromo-, hydrobromide; 4-Bromo-1,3-diazanaphthalene hydrobromide; 4-Bromoquinazoline HBr; 4-Br-Quinazoline•HBr; 1373223-20-1; 4-Bromoquinazoline monohydrobromide
EINECS	Contact for details

Quality Control

Our 4-Bromo-Quinazoline Hydrobromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and custom synthesis and purification to meet specific client requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.