Description

2-Oxo-2,3,5,6-Tetrahydrospiro[Indoline-3,4-Pyran]-5-Carboxylic Acid (Wx106147) is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic molecular architecture. This compound is of significant value for research and development in medicinal chemistry, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to construct novel heterocyclic compounds.
• Biochemical Research: Potential use as a tool compound or probe for investigating biological pathways and enzyme interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	2-Oxo-2,3,5,6-Tetrahydrospiro[Indoline-3,4-Pyran]-5-Carboxylic Acid (Wx106147)
CAS No.	1373028-72-8
Molecular Formula	C14H13NO4
Molecular Weight	259.26 g/mol
Synonyms	Wx106147; 5-Carboxy-2-oxo-2,3,5,6-tetrahydrospiro[indoline-3,4-pyran]; Spiro[indoline-3,4-pyran]-5-carboxylic acid, 2,3,5,6-tetrahydro-2-oxo-; 2-Oxospiro[indoline-3,4-pyran]-5-carboxylic acid, 2,3,5,6-tetrahydro-; 2-Oxo-2,3,5,6-tetrahydrospiro[indole-3,4-pyran]-5-carboxylic acid; 1373028-72-8; Spirocyclic indoline-pyran carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Oxo-2,3,5,6-Tetrahydrospiro[Indoline-3,4-Pyran]-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.