Description

Ethyl 5-Aminospiro[2.3]hexane-1-carboxylate (Wx101035) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting neurological disorders.
• Organic Synthesis Building Block: Utilized in medicinal chemistry for constructing complex spirocyclic scaffolds with potential biological activity.
• Research & Development (R&D): Serves as a critical material in academic and industrial labs for exploring new chemical entities and structure-activity relationships.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of APIs.
• Reference Standard: Used as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	Ethyl 5-Aminospiro[2.3]hexane-1-carboxylate (Wx101035)
CAS No.	1373028-53-5
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	Ethyl 5-aminospiro[2.3]hexane-1-carboxylate; 5-Aminospiro[2.3]hexane-1-carboxylic acid ethyl ester; WX-101035; Wx101035; 1-Carboxylic acid, 5-aminospiro[2.3]hexane-, ethyl ester; Ethyl 5-amino-1-spiro[2.3]hexanecarboxylate; 1373028-53-5
EINECS	Contact for details

Quality Control

Our Ethyl 5-Aminospiro[2.3]hexane-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.