Description

8-Boc-2-Iodoymethyl-1-Oxa-8-Azaspiro[4.5]Decane is a high-value, advanced pharmaceutical intermediate featuring a complex spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of potential drug candidates targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Spirocyclic Compound Library Synthesis: Essential for creating diverse chemical libraries featuring the privileged 1-oxa-8-azaspiro[4.5]decane structure for high-throughput screening.
• Neurological Drug Development: Employed in the research and synthesis of compounds targeting receptors and enzymes within the central nervous system.
• Process Chemistry & Scale-Up: Serves as a critical intermediate during the route development and optimization phase for scaling up API manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and development projects.
• Academic Research: Used in university and institutional labs for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	8-Boc-2-Iodoymethyl-1-Oxa-8-Azaspiro[4.5]Decane
CAS No.	1373028-07-9
Molecular Formula	C14H24INO3
Molecular Weight	381.25 g/mol
Synonyms	1-Oxa-8-azaspiro[4.5]decane, 2-(iodomethyl)-8-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl 2-(iodomethyl)-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; 8-Boc-2-(iodomethyl)-1-oxa-8-azaspiro[4.5]decane; 8-(tert-Butoxycarbonyl)-2-(iodomethyl)-1-oxa-8-azaspiro[4.5]decane; Boc-protected iodomethyl spirocyclic ether; 1373028-07-9 (CAS)
EINECS	Contact for details

Quality Control

Our 8-Boc-2-Iodoymethyl-1-Oxa-8-Azaspiro[4.5]Decane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.