Description

3-Hydroxy-3-Phenylazetidine Trifluoroacetate is a high-purity trifluoroacetate salt of a substituted azetidine, a valuable nitrogen-containing heterocyclic building block. This compound is essential for advanced pharmaceutical research and development, particularly in medicinal chemistry for creating novel drug candidates. It serves as a critical chiral intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs targeting various disease pathways.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with potentially novel modes of action.
• Fine Chemical Synthesis: Employed in the preparation of complex molecules, ligands for catalysis, and other specialty chemicals requiring the azetidine scaffold.
• Academic & R&D: Utilized in university and institutional laboratories for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	3-Hydroxy-3-Phenylazetidine Trifluoroacetate
CAS No.	1372173-52-8
Molecular Formula	C11H12F3NO3
Molecular Weight	263.21 g/mol
Synonyms	3-Phenyl-3-hydroxyazetidine trifluoroacetate; 3-Hydroxy-3-phenylazetidine TFA salt; 3-Phenylazetidin-3-ol trifluoroacetate; 3-Hydroxy-3-phenyl-1-azetidinium trifluoroacetate; Azetidine, 3-hydroxy-3-phenyl-, trifluoroacetate (1:1); 3-Phenyl-3-azetidinol trifluoroacetate; TFA salt of 3-Hydroxy-3-phenylazetidine
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-3-Phenylazetidine Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.