Description

3-(Piperidin-4-Yloxy)Benzenamine Hydrochloride is a high-purity organic salt building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its piperidine-oxyaniline scaffold.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological pathways and protein interactions.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	3-(Piperidin-4-Yloxy)Benzenamine Hydrochloride
CAS No.	1370365-89-1
Molecular Formula	C11H17ClN2O
Molecular Weight	228.72 g/mol
Synonyms	3-[(4-Piperidinyl)oxy]benzenamine hydrochloride; 3-(4-Piperidyloxy)aniline hydrochloride; 3-Aminophenyl 4-piperidinyl ether hydrochloride; 4-(3-Aminophenoxy)piperidine hydrochloride; Benzenamine, 3-(4-piperidinyloxy)-, hydrochloride; 3-(Piperidin-4-yloxy)phenylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-(Piperidin-4-Yloxy)Benzenamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.