Description

2-Chloro-1-Iodo-4-Isopropoxybenzene is a high-purity halogenated aromatic ether building block of significant interest in advanced organic synthesis. Its unique structure, featuring chlorine, iodine, and an isopropoxy group on a benzene ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aromatic core.
• Material Science: Serves as a building block for creating specialized monomers, ligands for catalysis, or liquid crystal compounds.
• Organic Synthesis: Employed in academic and industrial R&D for constructing complex, multi-substituted benzene derivatives and exploring new reaction pathways.
• Chemical Biology: Can be utilized as a probe or tag in bioconjugation chemistry due to the reactivity of the iodine moiety.

Basic Information

Product Name	2-Chloro-1-Iodo-4-Isopropoxybenzene
CAS No.	1369830-17-0
Molecular Formula	C9H10ClIO
Molecular Weight	296.53 g/mol
Synonyms	1-Chloro-2-iodo-4-isopropoxybenzene; 4-Isopropoxy-2-chloro-1-iodobenzene; 2-Chloro-4-isopropoxy-1-iodobenzene; Benzene, 2-chloro-1-iodo-4-(1-methylethoxy)-; 2-Chloro-1-iodo-4-(propan-2-yloxy)benzene (IUPAC); 4-(Isopropoxy)-2-chloroiodobenzene; 1-Iodo-2-chloro-4-isopropoxybenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-Iodo-4-Isopropoxybenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with your specifications. Our quality commitment supports applications requiring high-purity building blocks for sensitive R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Typical 98-99%)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.