Description

Acetamide, 2-[3-[6-Ethoxy-4-[[4-(1H-Pyrazol-4-Yl)Phenyl]Amino]-2-Quinazolinyl]Phenoxy]-n-(1-Methylethyl)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of targeted therapeutic agents, particularly in oncology. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of targeted kinase inhibitors for cancer therapy research.
• Biochemical Research: Used as a reference standard or probe molecule in enzymatic and cellular assay development.
• Preclinical Development: Serves as a crucial precursor in the scale-up and process optimization for new chemical entities (NCEs).
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) in medicinal chemistry.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	Acetamide, 2-[3-[6-Ethoxy-4-[[4-(1H-Pyrazol-4-Yl)Phenyl]Amino]-2-Quinazolinyl]Phenoxy]-n-(1-Methylethyl)-
CAS No.	1369452-53-8
Molecular Formula	C30H29N7O3
Molecular Weight	535.60 g/mol
Synonyms	N-Isopropyl-2-[3-[6-ethoxy-4-[[4-(1H-pyrazol-4-yl)phenyl]amino]quinazolin-2-yl]phenoxy]acetamide; 2-(3-(6-Ethoxy-4-((4-(1H-pyrazol-4-yl)phenyl)amino)quinazolin-2-yl)phenoxy)-N-isopropylacetamide; UNII-9K9V4FZ1QK; 9K9V4FZ1QK; A selective kinase inhibitor intermediate; 4-Anilinoquinazoline derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems (ISO 9001) with analytical methods validated for accuracy and precision. Every batch is characterized by HPLC, NMR, and LC-MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance for your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This material is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if possible.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.