Description

2-Cyclobutylisonicotinic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1369158-34-8. This compound is valued for its unique cyclobutyl-substituted pyridinecarboxylic acid structure, which serves as a critical building block in modern medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its heterocyclic framework for bioactivity.
• Ligand Synthesis: Serves as a versatile starting material for creating specialized ligands in catalytic and coordination chemistry.
• Chemical Biology Probes: Employed in the construction of molecular probes for studying enzyme function and protein interactions.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with tailored thermal or optical properties.

Basic Information

Product Name	2-Cyclobutylisonicotinic Acid
CAS No.	1369158-34-8
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	2-Cyclobutylpyridine-4-carboxylic Acid; 4-Pyridinecarboxylic acid, 2-cyclobutyl-; Isonicotinic acid, 2-cyclobutyl-; 2-Cyclobutyl-4-pyridinecarboxylic Acid; 2-Cyclobutylisonicotinate; Cyclobutylpyridinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Cyclobutylisonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.