Description

9-Bromo-2,3,4,5-tetrahydro-1-benzoxepine is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its reactive bromine atom and fused ring system.
• Ligand and Catalyst Development: Acts as a starting material for creating novel phosphine or nitrogen-based ligands used in transition metal catalysis.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers with specific electronic or optical properties.
• Chemical Biology Probes: Useful for creating tagged molecules or photoaffinity labels for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	9-Bromo-2,3,4,5-tetrahydro-1-benzoxepine
CAS No.	1369140-29-3
Molecular Formula	C11H13BrO
Molecular Weight	241.13 g/mol
Synonyms	9-Bromo-2,3,4,5-tetrahydro-1-benzoxepin; 1-Benzoxepine, 9-bromo-2,3,4,5-tetrahydro-; 9-Bromo-2,3,4,5-tetrahydrobenzo[b]oxepine; 9-Bromotetrahydro-1-benzoxepine; 2,3,4,5-Tetrahydro-9-bromo-1-benzoxepine
EINECS	Contact for details

Quality Control

Our 9-Bromo-2,3,4,5-tetrahydro-1-benzoxepine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.