Description

1-(4-Fluorobenzyl)-1H-Imidazole-4-Carboxylic Acid CAS NO 1368524-71-3 is a high-value fluorinated imidazole derivative, a key building block in modern pharmaceutical and agrochemical research. Its molecular structure, featuring both a fluorobenzyl group and a carboxylic acid functionality, makes it a versatile intermediate for synthesizing novel active compounds. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate this specific heterocyclic scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new-generation fungicides, herbicides, and plant growth regulators where the imidazole core provides bioactive properties.
• Chemical Biology & Proteomics: Serves as a building block for designing chemical probes, enzyme inhibitors, and molecular tags used in biochemical assays and target identification.
• Material Science: Can be utilized in the synthesis of specialized ligands for catalysis or as a monomer for creating functional polymers with specific electronic or binding characteristics.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific synthesis projects requiring this precise fluorinated structure.

Basic Information

Product Name	1-(4-Fluorobenzyl)-1H-Imidazole-4-Carboxylic Acid
CAS No.	1368524-71-3
Molecular Formula	C11H9FN2O2
Molecular Weight	220.20 g/mol
Synonyms	1-[(4-Fluorophenyl)methyl]-1H-imidazole-4-carboxylic acid; 1H-Imidazole-4-carboxylic acid, 1-[(4-fluorophenyl)methyl]-; 4-Fluorobenzylimidazole-4-carboxylic Acid; 1-(4-Fluorobenzyl)imidazole-4-carboxylic Acid; 1-(p-Fluorobenzyl)-1H-imidazole-4-carboxylic Acid; 1368524-71-3; 1-(4-Fluorobenzyl)-1H-imidazole-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzyl)-1H-Imidazole-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.