Description

3-Chloroisothiazole-5-Carboxylic Acid is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecules, particularly in the development of advanced pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, leveraging the bioactive isothiazole scaffold.
• Material Science Research: Serves as a precursor for functional polymers, ligands, or advanced organic materials requiring specific heterocyclic motifs.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes, enzyme inhibitors, or bioconjugation reagents.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploring new chemical reactions in heterocyclic chemistry.

Basic Information

Product Name	3-Chloroisothiazole-5-Carboxylic Acid
CAS No.	1368382-15-3
Molecular Formula	C4H2ClNO2S
Molecular Weight	163.58 g/mol
Synonyms	5-Carboxy-3-chloroisothiazole; 3-Chloro-1,2-thiazole-5-carboxylic acid; 3-Chloro-5-isothiazolecarboxylic acid; 3-Chloro-1,2-thiazole-5-carboxylic acid; 3-Chloroisothiazole-5-carboxylic acid; 3-Chloro-5-carboxyisothiazole; 3-Chloro-1,2-thiazole-5-carboxylic acid (9CI); 3-Chloro-5-isothiazolecarboxylic acid (ACD/Name 4.0)
EINECS	Contact for details

Quality Control

Our 3-Chloroisothiazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.