Description

2-Azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid is a high-value, bicyclic organic compound featuring a carboxylic acid functional group integrated into a constrained, nitrogen-containing bridged ring system. This unique structural motif makes it a critical chiral building block and intermediate for the synthesis of complex molecules, particularly in advanced pharmaceutical research. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors, neurological agents, and antiviral compounds.
• Agrochemical Research: Used in the development of advanced herbicides, fungicides, and insecticides that require specific stereochemistry for biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Potential building block for advanced polymers and functional materials with specific structural properties.
• Academic & Industrial R&D: Employed in chemical research for studying reaction mechanisms and developing new synthetic methodologies involving constrained ring systems.

Basic Information

Product Name	2-Azabicyclo[2.2.1]hept-5-ene-3-carboxylic Acid
CAS No.	1367697-62-8
Molecular Formula	C7H9NO2
Molecular Weight	139.15 g/mol
Synonyms	1-Aza-4-aminonorbornane-5-carboxylic acid; 2-Azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid; 3-Carboxy-2-azabicyclo[2.2.1]hept-5-ene; 5-Norbornene-2-carboxylic acid, 1-aza-4-amino-; (1R,4S)-2-Azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid (for enantiopure form); Bicyclic β-amino acid derivative; 2-Azanorbornene-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 2-Azabicyclo[2.2.1]hept-5-ene-3-carboxylic acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess (where applicable), and spectroscopic identification. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP standards for advanced intermediates. Specifications can be customized to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for enantiopure grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.