Description

(1R,4R)-n-(2-Fluoro-Benzyl)-Cyclohexane-1,4-Diamine Hydrochloride is a high-purity chiral diamine hydrochloride salt, valued as a critical building block in advanced organic synthesis. Its defined stereochemistry and functional groups make it an essential intermediate for developing novel pharmaceutical compounds and fine chemicals. This product is primarily targeted at research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Ligand Synthesis: Used in the preparation of chiral ligands for asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a precursor in the synthesis of novel herbicides, fungicides, and plant growth regulators with specific stereochemical requirements.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals where precise molecular architecture is crucial.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(1R,4R)-n-(2-Fluoro-Benzyl)-Cyclohexane-1,4-Diamine Hydrochloride
CAS No.	1366386-69-7
Molecular Formula	C₁₃H₂₀ClFN₂
Molecular Weight	258.76 g/mol
Synonyms	(1R,4R)-N-[(2-Fluorophenyl)methyl]cyclohexane-1,4-diamine hydrochloride; (1R,4R)-N-(2-Fluorobenzyl)cyclohexane-1,4-diamine HCl; (1R,4R)-2-Fluoro-N-[(1R,4R)-4-aminocyclohexyl]benzylamine hydrochloride; trans-N-(2-Fluorobenzyl)cyclohexane-1,4-diamine hydrochloride; (1R,4R)-1,4-Diaminocyclohexane, N-(2-fluorobenzyl)-, hydrochloride; 1366386-69-7; (1R,4R)-FBCD HCl
EINECS	Contact for details

Quality Control

Our (1R,4R)-n-(2-Fluoro-Benzyl)-Cyclohexane-1,4-Diamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.