Description

Jwh 387 is a synthetic cannabinoid receptor agonist of significant interest in pharmacological research. This compound is valued for its high binding affinity and selectivity, making it a critical tool for studying the endocannabinoid system. Researchers in pharmaceutical development, neuroscience, and analytical chemistry utilize this reference standard to investigate receptor interactions, metabolic pathways, and for method development and validation.

Application

• Pharmacological Research: Used as a reference standard in studies targeting the CB1 and CB2 cannabinoid receptors to understand signaling pathways and therapeutic potentials.
• Neuroscience Studies: Employed in preclinical research to investigate the effects of cannabinoid receptor modulation on neurological functions and behaviors.
• Analytical Chemistry: Serves as a high-purity certified reference material (CRM) for the calibration of equipment and validation of analytical methods such as HPLC, GC-MS, and LC-MS.
• Metabolic Pathway Investigation: Utilized in in vitro and in vivo studies to identify and characterize primary and secondary metabolites.
• Forensic Science: Acts as an analytical standard for the identification and quantification of novel psychoactive substances (NPS) in forensic casework.
• Biochemical Assay Development: Applied in the development and optimization of high-throughput screening assays for drug discovery pipelines.

Basic Information

Product Name	Jwh 387
CAS No.	1366067-59-5
Molecular Formula	C24H23NO3
Molecular Weight	373.45 g/mol
Synonyms	JWH-387; 1-Pentyl-3-(4-chloro-1-naphthoyl)indole; 1-Pentyl-1H-indol-3-yl-(4-chloronaphthalen-1-yl)methanone; (4-Chloro-1-naphthoyl)-1-pentylindole; JWH 387; JWH387; AM-387
EINECS	Contact for details

Quality Control

Every batch of Jwh 387 is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.