Description

1-(Pyridin-2-Yl)Azetidin-3-Amine Trihydrochloride is a high-purity, pharmaceutically relevant organic salt used as a critical building block in medicinal chemistry. Its value lies in its role as a versatile intermediate for the synthesis of novel bioactive compounds, particularly in drug discovery programs targeting a range of therapeutic areas. This compound is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality intermediates for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead compound optimization due to its azetidine and pyridine motifs.
• Chemical Biology Probes: Serves as a precursor for designing molecular probes to study biological pathways and enzyme functions.
• Library Synthesis: Employed in combinatorial and parallel synthesis to create diverse compound libraries for high-throughput screening.
• Process Chemistry: Utilized in route scouting and process development for the scalable manufacture of target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and development projects.

Basic Information

Product Name	1-(Pyridin-2-Yl)Azetidin-3-Amine Trihydrochloride
CAS No.	1365968-67-7
Molecular Formula	C8H14Cl3N3
Molecular Weight	266.57 g/mol
Synonyms	1-(2-Pyridinyl)-3-azetidinamine trihydrochloride; 3-Amino-1-(pyridin-2-yl)azetidine trihydrochloride; 1-(Pyridin-2-yl)azetidin-3-amine hydrochloride (1:3); Azetidin-3-amine, 1-(2-pyridinyl)-, trihydrochloride; 1365968-67-7; 1-(2-Pyridyl)azetidin-3-amine trihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Pyridin-2-Yl)Azetidin-3-Amine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.