Description

Fluoromethyl 2-Pyridyl Sulfone is a specialized organosulfur compound featuring a sulfone group linked to a fluoromethyl moiety and a pyridyl ring. This unique structure makes it a valuable building block and reagent in advanced synthetic chemistry, particularly for introducing fluorinated sulfone functionalities. It is primarily utilized by pharmaceutical and agrochemical R&D teams engaged in the discovery and process development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, especially those targeting kinase inhibition or requiring fluorinated motifs for metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the sulfone and fluorine groups can enhance biological activity and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced materials with specific surface properties.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in metal-catalyzed reactions (e.g., Suzuki, Negishi) to construct biaryl systems.
• Fluorination Chemistry: Employed as a source of the -CH2F group in nucleophilic substitution or radical reactions to incorporate fluorine atoms into target molecules.
• Ligand and Catalyst Development: Useful for modifying pyridine-based ligands to tune the electronic and steric properties of metal complexes.

Basic Information

Product Name	Fluoromethyl 2-Pyridyl Sulfone
CAS No.	1365765-53-2
Molecular Formula	C6H6FNO2S
Molecular Weight	175.18 g/mol
Synonyms	2-((Fluoromethyl)sulfonyl)pyridine; (Fluoromethyl)(pyridin-2-yl)sulfone; 2-Pyridinesulfonic acid, fluoromethyl ester; Fluoromethyl 2-pyridylsulfone; 2-(Fluoromethylsulfonyl)pyridine; Pyridine, 2-((fluoromethyl)sulfonyl)-; Fluoromethylsulfonyl pyridine
EINECS	Contact for details

Quality Control

Our Fluoromethyl 2-Pyridyl Sulfone is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.