Description

Jwh 412 is a synthetic cannabinoid receptor agonist of significant interest in pharmacological research and chemical synthesis. This compound, identified by CAS NO 1364933-59-4, is a critical tool for scientists investigating the endocannabinoid system and its complex interactions. It is primarily utilized by research institutions, pharmaceutical development laboratories, and specialized chemical manufacturers requiring high-purity reference standards and intermediates.

Application

• Pharmacological Research: Used as a reference standard and active agent in preclinical studies to investigate cannabinoid receptor (CB1/CB2) binding affinity, signaling pathways, and physiological effects.

• Biochemical Assay Development: Serves as a key ligand in the development and validation of high-throughput screening (HTS) assays for drug discovery programs targeting the endocannabinoid system.

• Metabolic Pathway Studies: Employed in in vitro and in vivo studies to understand the metabolism, pharmacokinetics, and toxicological profile of synthetic cannabinoids.

• Chemical Synthesis Intermediate: Acts as a sophisticated building block or precursor in the multi-step synthesis of novel chemical entities for advanced research purposes.

• **| Item | Detail |
  | --- | --- |
  | Product Name | Jwh 412 |
  | CAS No. | 1364933-59-4 |
  | Molecular Formula | Contact for details |
  | Molecular Weight | Contact for details |
  | Synonyms | JWH-412; 1-Pentyl-3-(4-chloro-1-naphthoyl)indole; 1-Pentyl-3-(4-chloronaphthalene-1-carbonyl)-1H-indole; 4-Chloro-1-naphthoyl-1-pentylindole; JWH 412; JWH412 |
  | EINECS | Contact for details |

  Quality Control

  Every batch of Jwh 412 is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) that detail the results of advanced analytical testing, including HPLC for purity and spectroscopic methods for structural confirmation. Our commitment to reliable supply and documentation integrity supports critical research and development workflows.

  Storage

  Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

  Specification

  Item	Specification
  Appearance	Off-white to beige powder
  Identification (IR)	Conforms to structure
  Purity (HPLC)	≥ 98%
  Related Substances (HPLC)	Total impurities ≤ 2.0%
  Residual Solvents (GC)	Complies with ICH guidelines
  Loss on Drying	≤ 0.5%

  Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.**