Description

(1S)-6-Methoxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline is a chiral tetrahydroisoquinoline derivative, a privileged scaffold in medicinal chemistry. This compound matters as a key chiral building block for the synthesis of complex pharmaceutical agents, offering precise stereochemical control. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) drugs, alkaloid-based therapeutics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel drug candidates, particularly in neuroscience and oncology.
• Medicinal Chemistry Research: Serves as a core scaffold for constructing libraries of compounds to explore structure-activity relationships (SAR).
• Alkaloid Synthesis: Used in the semi-synthesis or total synthesis of complex natural products and alkaloids with biological activity.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in catalytic asymmetric reactions to introduce stereogenic centers.
• Reference Standard: Utilized as an analytical standard in quality control and method development for pharmaceutical manufacturing.

Basic Information

Product Name	(1S)-6-Methoxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline
CAS No.	1364891-68-8
Molecular Formula	C11H15NO
Molecular Weight	177.24 g/mol
Synonyms	(S)-6-Methoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline; (1S)-6-Methoxy-1-methyl-3,4-dihydro-1H-isoquinoline; (-)-6-Methoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline; (S)-1-Methyl-6-methoxy-1,2,3,4-tetrahydroisoquinoline; 1H-Isoquinoline, 1,2,3,4-tetrahydro-6-methoxy-1-methyl-, (1S)-; (S)-MMTIQ
EINECS	Contact for details

Quality Control

Our (1S)-6-Methoxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.