Description

5-Iodo-1,7-Naphthyridin-8(7H)-One is a high-purity, halogenated naphthyridinone derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, functionalized scaffold for constructing complex heterocyclic systems, particularly in pharmaceutical discovery and materials science. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable building blocks for drug candidate synthesis and novel material development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research programs.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products.
• Chemical Biology Probe: Serves as a precursor for labeled compounds or molecular probes used in biological target identification and validation.
• Organic Light-Emitting Diode (OLED) Materials: A potential intermediate for electron-transport or host materials in advanced display technologies.
• Ligand Synthesis: Useful for constructing complex chelating ligands in coordination chemistry and catalysis.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and novel heterocycle synthesis.

Basic Information

Product Name	5-Iodo-1,7-Naphthyridin-8(7H)-One
CAS No.	1363405-29-1
Molecular Formula	C8H5IN2O
Molecular Weight	272.04 g/mol
Synonyms	5-Iodo-7H-1,7-naphthyridin-8-one; 5-Iodo-1,7-naphthyridin-8-ol; 8-Hydroxy-5-iodo-1,7-naphthyridine; 1363405-29-1; 5-Iodo-8-oxo-7,8-dihydro-1,7-naphthyridine; 5-Iodo-7H-[1,7]naphthyridin-8-one; 5-Iodo-1,7-dihydronaphthyridin-8-one
EINECS	Contact for details

Quality Control

Our 5-Iodo-1,7-Naphthyridin-8(7H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.