Description

3-(Aminomethyl)Cyclobutanone Hydrochloride is a specialized organic salt of significant interest in advanced chemical synthesis. This compound serves as a valuable bifunctional building block, offering both a protected amine and a reactive ketone group within a strained cyclobutane ring system. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel molecular architectures and exploring new chemical space.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting the central nervous system (CNS) or possessing complex cyclic scaffolds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the cyclobutane moiety can impart unique biological activity and stability.
• Chemical Biology Probe Synthesis: Employed for creating molecular probes and linkers in drug discovery, leveraging its reactive handles for conjugation and labeling.
• Material Science: Acts as a monomer or cross-linking agent in the research and development of specialty polymers with tailored thermal or mechanical properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, including ring-opening, cycloaddition, and asymmetric synthesis research.

Basic Information

Product Name	3-(Aminomethyl)Cyclobutanone Hydrochloride
CAS No.	1363382-42-6
Molecular Formula	C6H12ClNO
Molecular Weight	149.62 g/mol
Synonyms	3-(Aminomethyl)cyclobutan-1-one hydrochloride; Cyclobutanone, 3-(aminomethyl)-, hydrochloride; 1-(Aminomethyl)cyclobutan-3-one hydrochloride; 3-(Aminomethyl)-1-cyclobutanone HCl; 3-Carbamoylcyclobutylamine hydrochloride (tautomeric form); Aminomethyl cyclobutanone HCl
EINECS	Contact for details

Quality Control

Our 3-(Aminomethyl)Cyclobutanone Hydrochloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.