Description

cis-1,3-Cyclobutanediamine is a high-purity, stereochemically defined diamine building block essential for advanced organic synthesis. Its rigid cyclobutane backbone and two strategically positioned primary amine groups make it a valuable precursor for constructing complex molecular architectures with defined spatial orientation. This compound is particularly sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for developing novel active ingredients, chiral ligands, and functional polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chiral Ligand & Catalyst Preparation: Serves as a backbone for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer & Material Science: A monomer for producing specialty polyamides, polyurethanes, and epoxy curing agents with enhanced thermal and mechanical properties.
• Chemical Research & Development: A versatile building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Chelating Agent Precursor: Used to synthesize complexing agents for metal ion sequestration and catalysis.

Basic Information

Product Name	cis-1,3-Cyclobutanediamine
CAS No.	1363382-21-1
Molecular Formula	C4H10N2
Molecular Weight	86.14 g/mol
Synonyms	(1R,3S)-1,3-Cyclobutanediamine; (1S,3R)-1,3-Cyclobutanediamine; cis-1,3-Diaminocyclobutane; rel-(1R,3S)-1,3-Cyclobutanediamine; 1,3-Cyclobutanediamine, cis-; Cyclobutane-1,3-diamine, (1R,3S)-rel-; UNII-9Q9K3V8A7F
EINECS	Contact for details

Quality Control

Our cis-1,3-Cyclobutanediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.