Description

6-Amino-2-Boc-2-Azaspiro[4.5]Decane is a high-purity, protected spirocyclic amine building block of significant importance in modern organic synthesis. This compound is valued for its rigid, three-dimensional structure, which is crucial for developing novel pharmacophores and fine-tuning the biological activity of drug candidates. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and combinatorial chemistry libraries to explore new chemical space.
• Process Chemistry: Serves as a critical intermediate in the scalable, multi-step synthesis of complex target molecules under GMP conditions.
• Agrochemical Research: Employed in the development of new pesticides and herbicides, leveraging its spirocyclic scaffold for enhanced activity.
• Chemical Biology: Acts as a precursor for probes and ligands used to study enzyme function and receptor binding.
• Academic Research: Utilized in universities and research institutes for methodological development in synthetic organic chemistry.

Basic Information

Product Name	6-Amino-2-Boc-2-Azaspiro[4.5]Decane
CAS No.	1363382-19-7
Molecular Formula	C14H26N2O2
Molecular Weight	254.37 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-2-azaspiro[4.5]decan-6-amine; tert-Butyl 6-amino-2-azaspiro[4.5]decane-2-carboxylate; 2-Boc-2-Azaspiro[4.5]decan-6-amine; 6-Amino-2-[(tert-butoxycarbonyl)amino]-2-azaspiro[4.5]decane; 2-Azaspiro[4.5]decan-6-amine, 2-[(1,1-dimethylethoxy)carbonyl]-; 2-Boc-6-Amino-2-azaspiro[4.5]decane; 6-Amino-2-Boc-2-azaspiro[4.5]decane; 2-(tert-Butoxycarbonyl)-2-azaspiro[4.5]decan-6-amine
EINECS	Contact for details

Quality Control

Our 6-Amino-2-Boc-2-Azaspiro[4.5]Decane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with GMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.