Description

2-Cbz-6-Oxo-2-Azaspiro[3.3]Heptane is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic scaffold class. This compound is a critical building block in modern medicinal chemistry, valued for its unique three-dimensional structure that enables the development of novel bioactive molecules with improved properties. It is primarily utilized by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of new drug candidates, particularly in areas targeting central nervous system disorders and other therapeutic applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional molecules for targeted protein degradation.
• CNS Drug Discovery: Applied in the synthesis of potential therapeutics for neurological and psychiatric conditions due to its spirocyclic architecture.
• Chemical Biology Probes: Utilized to create tool compounds for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-fidelity, complex organic intermediates.

Basic Information

Product Name	2-Cbz-6-Oxo-2-Azaspiro[3.3]Heptane
CAS No.	1363381-91-2
Molecular Formula	C14H15NO3
Molecular Weight	245.27 g/mol
Synonyms	2-[(Benzyloxy)carbonyl]-2-azaspiro[3.3]heptan-6-one; 2-Carbobenzyloxy-6-oxo-2-azaspiro[3.3]heptane; 2-Azaspiro[3.3]heptan-6-one, 2-[(phenylmethoxy)carbonyl]-; 2-Cbz-2-azaspiro[3.3]heptan-6-one; Benzyl 6-oxo-2-azaspiro[3.3]heptane-2-carboxylate; Spiro[3.3]heptane-6-one, 2-[(benzyloxy)carbonyl]-2-aza-
EINECS	Contact for details

Quality Control

Our 2-Cbz-6-Oxo-2-Azaspiro[3.3]Heptane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your most sensitive R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.