Description

3-(3-Bromophenyl)Oxetane-3-Carboxylic Acid is a high-value, multifunctional oxetane building block used in advanced organic synthesis. This compound is critical for medicinal chemistry and materials science research, enabling the introduction of both a carboxylic acid and a strained oxetane ring into molecular scaffolds. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for developing novel active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker component due to its bifunctional oxetane-carboxylic acid structure.
• Polymer Modification: Used to incorporate oxetane monomers into polymer backbones to enhance thermal stability and modify material properties.
• Agrochemical Synthesis: Employed in the research and development of advanced crop protection agents.
• Ligand and Catalyst Design: Useful for creating novel chelating agents and organocatalysts in asymmetric synthesis.
• Academic & Industrial R&D: A valuable reagent for exploring new chemical space and reaction methodologies in organic chemistry.

Basic Information

Product Name	3-(3-Bromophenyl)Oxetane-3-Carboxylic Acid
CAS No.	1363381-80-9
Molecular Formula	C10H9BrO3
Molecular Weight	257.08 g/mol
Synonyms	3-(3-Bromophenyl)-3-oxetanecarboxylic acid; 3-(3-Bromophenyl)oxetane-3-carboxylic acid; 3-Bromo-α,α-dimethylbenzenepropanoic acid, oxetane derivative; 3-(3-Bromophenyl)oxetane-3-carboxylate; 1363381-80-9; 3-(3-Bromophenyl)-oxetane-3-carboxylic acid; 3-(3-Bromophenyl)-3-carboxyoxetane
EINECS	Contact for details

Quality Control

Our production of 3-(3-Bromophenyl)Oxetane-3-Carboxylic Acid adheres to strict quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for advanced intermediates intended for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.