Description

7-Thia-2-Aza-Spiro[3.5]Nonane 7,7-Dioxide Hemioxalate is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic sulfonamide structure. This compound is of significant value for research and development in medicinal chemistry, particularly for constructing complex molecular scaffolds. It is primarily sought by pharmaceutical companies and contract research organizations (CROs) engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Spirocyclic Compound Library Synthesis: Serves as a core scaffold for generating diverse compound libraries for high-throughput screening.
• Protease Inhibitor Development: The sulfonamide moiety makes it a relevant precursor for developing enzyme inhibitors.
• Chemical Biology Probes: Utilized in the design of molecular probes to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of target molecules.

Basic Information

Item	Details
Product Name	7-Thia-2-Aza-Spiro[3.5]Nonane 7,7-Dioxide Hemioxalate
CAS No.	1363381-31-0
Molecular Formula	C9H13NO7S
Molecular Weight	279.27 g/mol
Synonyms	7-Thia-2-aza-spiro[3.5]nonane 7,7-dioxide hemioxalate; 2-Aza-7-thiaspiro[3.5]nonane 7,7-dioxide hemioxalate; Spiro[3.5]nonane-7-thia-2-aza-7,7-dioxide hemioxalate; 1-Oxa-4-thia-8-azaspiro[4.4]nonane 4,4-dioxide hemioxalate; 1,4-Thiazepane-4,4-dioxide, hexahydro-, hemioxalate; Pharmaceutical Intermediate 1363381-31-0
EINECS	Contact for details

Quality Control

Our 7-Thia-2-Aza-Spiro[3.5]Nonane 7,7-Dioxide Hemioxalate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specified parameters. We support development and cGMP requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.