Description

trans-3-Hydroxy-3-Methylcyclobutylamine Hydrochloride is a high-purity, pharmaceutically relevant chiral amine hydrochloride salt. This compound serves as a critical chiral building block and intermediate in modern organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex molecules. The product is supplied with full analytical documentation to ensure batch-to-batch consistency for demanding applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Process Chemistry: Serves as a starting material or intermediate in the scalable synthesis of target drug candidates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor to introduce stereochemical complexity into organic molecules.
• Chemical Research: Utilized in academic and industrial R&D for exploring new synthetic methodologies and reaction pathways.
• Reference Standard: Suitable for use as an analytical standard in quality control laboratories.

Basic Information

Product Name	trans-3-Hydroxy-3-Methylcyclobutylamine Hydrochloride
CAS No.	1363381-26-3
Molecular Formula	C6H14ClNO
Molecular Weight	151.63 g/mol
Synonyms	(1r,3r)-3-Amino-3-methylcyclobutanol hydrochloride; trans-3-Amino-3-methylcyclobutanol hydrochloride; (1R,3R)-3-Hydroxy-3-methylcyclobutanamine hydrochloride; 3-Methyl-3-aminocyclobutanol hydrochloride (trans); Cyclobutanamine, 3-hydroxy-3-methyl-, hydrochloride, (1R,3R)-; trans-3-Methyl-3-aminocyclobutanol HCl
EINECS	Contact for details

Quality Control

Our trans-3-Hydroxy-3-Methylcyclobutylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.