Description

1-(Aminomethyl)-Cyclobutanecarboxylicacidhydrochloride is a high-purity, synthetically valuable building block in organic chemistry. This compound is crucial for the development of novel active pharmaceutical ingredients (APIs) and advanced materials due to its unique cyclobutane scaffold and functionalized amine group. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Peptide Mimetics & Conformationally Restricted Analogs: Used to introduce the rigid cyclobutane ring into peptide chains, modifying their biological activity, stability, and pharmacokinetic properties.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and insecticides with potentially improved efficacy and environmental profiles.
• Ligand Synthesis for Catalysis: Employed in the preparation of novel chiral ligands and catalysts for asymmetric synthesis applications.
• Material Science: A potential monomer or cross-linking agent for creating polymers with specific thermal or mechanical properties.
• Chemical Biology Probes: Useful for labeling and studying biological systems due to its reactive amine handle.

Basic Information

Product Name	1-(Aminomethyl)-Cyclobutanecarboxylicacidhydrochloride
CAS No.	1360547-44-9
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	1-(Aminomethyl)cyclobutanecarboxylic acid hydrochloride; Cyclobutanecarboxylic acid, 1-(aminomethyl)-, hydrochloride; 1-(Aminomethyl)cyclobutane-1-carboxylic acid hydrochloride; (1-(Aminomethyl)cyclobutyl)formic acid hydrochloride; Aminomethylcyclobutanecarboxylic acid HCl
EINECS	Contact for details

Quality Control

Our 1-(Aminomethyl)-Cyclobutanecarboxylicacidhydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and can support regulatory filings with necessary documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.