Description

2,2,2-Trifluoro-n-(Piperidin-4-Ylmethyl)Ethanamine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold with a trifluoroethylamine moiety. This compound matters for its critical role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material to develop next-generation therapeutics, leveraging its unique structural properties to modulate drug potency and pharmacokinetics.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its piperidine core and fluorine substitution.
• API Development: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs), especially in CNS and oncology fields.
• Chemical Biology Probes: Utilized in the development of tool compounds and probes for studying biological targets and pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule fabrication.
• Process Chemistry: Integral in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.

Basic Information

Product Name	2,2,2-Trifluoro-n-(Piperidin-4-Ylmethyl)Ethanamine Dihydrochloride
CAS No.	1357923-41-1
Molecular Formula	C9H18Cl2F3N2
Molecular Weight	279.15 g/mol
Synonyms	4-[(2,2,2-Trifluoroethylamino)methyl]piperidine dihydrochloride; 1-(Piperidin-4-ylmethylamino)-2,2,2-trifluoroethane dihydrochloride; 2,2,2-Trifluoro-N-(piperidin-4-ylmethyl)ethan-1-amine dihydrochloride; N-[(4-Piperidinyl)methyl]-2,2,2-trifluoroethylamine dihydrochloride; 2,2,2-Trifluoro-N-(4-piperidinylmethyl)ethanamine dihydrochloride; 1357923-41-1; 2,2,2-Trifluoroethyl-(4-piperidylmethyl)amine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-n-(Piperidin-4-Ylmethyl)Ethanamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.